Biotechnology for Neuroscience

Selected research products

Leto K, Arancillo M, Becker EB, Buffo A, Chiang C, Ding B, Dobyns WB, Dusart I, Haldipur P, Hatten ME, Hoshino M, Joyner AL, Kano M, Kilpatrick DL, Koibuchi N, Marino S, Martinez S, Millen KJ, Millner TO, Miyata T, Parmigiani E, Schilling K, Sekerkova G, Sillitoe RV, Sotelo C, Uesaka N, Wefers A, Wingate RJ, Hawkes R. (2015) Consensus Paper: Cerebellar Development. Cerebellum (London, England) [DOI  PMID]

Parmigiani E, Leto K, Rolando C, Figueres-Onate M, Lopez-Mascaraque L, Buffo A, Rossi F. (2015) Heterogeneity and Bipotency of Astroglial-Like Cerebellar Progenitors along the Interneuron and Glial Lineages. The Journal of neuroscience : the official journal of the Society for Neuroscience 35(19) 7388-402 [DOI  PMID]

Nato G, Caramello A, Trova S, Avataneo V, Rolando C, Taylor V, Buffo A, Peretto P, Luzzati F. (2015) Striatal astrocytes produce neuroblasts in an excitotoxic model of Huntington's disease. Development (Cambridge, England) 142(5) 840-5 [DOI  PMID]

Leto K, Carulli D, Buffo A. (2014) Symposium in honor of Ferdinando Rossi: a passionate journey through the cerebellar mysteries. Cerebellum (London, England) 13(6) 791-4 [PMID]

De Luca A, Parmigiani E, Tosatto G, Martire S, Hoshino M, Buffo A, Leto K, Rossi F. (2015) Exogenous Sonic hedgehog modulates the pool of GABAergic interneurons during cerebellar development. Cerebellum (London, England) 14(2) 72-85 [DOI  PMID]

Boda E, Di Maria S, Rosa P, Taylor V, Abbracchio MP, Buffo A. (2015) Early phenotypic asymmetry of sister oligodendrocyte progenitor cells after mitosis and its modulation by aging and extrinsic factors. Glia 63(2) 271-86 [DOI  PMID]

Boda E, Buffo A. (2014) Beyond cell replacement: unresolved roles of NG2-expressing progenitors. Frontiers in neuroscience 8 122 [DOI  PMID]

Boccazzi M, Rolando C, Abbracchio MP, Buffo A, Ceruti S. (2014) Purines regulate adult brain subventricular zone cell functions: contribution of reactive astrocytes. Glia 62(3) 428-39 [DOI  PMID]

Buffo A, Rossi F. (2013) Origin, lineage and function of cerebellar glia. Progress in neurobiology 109 42-63 [DOI  PMID]

Fratangeli A, Parmigiani E, Fumagalli M, Lecca D, Benfante R, Passafaro M, Buffo A, Abbracchio MP, Rosa P. (2013) The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells. The Journal of biological chemistry 288(7) 5241-56 [DOI  PMID]

Rolando C, Parolisi R, Boda E, Schwab ME, Rossi F, Buffo A. (2012) Distinct roles of Nogo-a and Nogo receptor 1 in the homeostatic regulation of adult neural stem cell function and neuroblast migration. The Journal of neuroscience : the official journal of the Society for Neuroscience 32(49) 17788-99 [DOI  PMID]

Behrendt G, Baer K, Buffo A, Curtis MA, Faull RL, Rees MI, Gotz M, Dimou L. (2013) Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men. Glia 61(2) 273-86 [DOI  PMID]

Boda E, Vigano F, Rosa P, Fumagalli M, Labat-Gest V, Tempia F, Abbracchio MP, Dimou L, Buffo A. (2011) The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage. Glia 59(12) 1958-73 [DOI  PMID]

Ceruti S, Vigano F, Boda E, Ferrario S, Magni G, Boccazzi M, Rosa P, Buffo A, Abbracchio MP. (2011) Expression of the new P2Y-like receptor GPR17 during oligodendrocyte precursor cell maturation regulates sensitivity to ATP-induced death. Glia 59(3) 363-78 [DOI  PMID]

Kronenberg G, Gertz K, Cheung G, Buffo A, Kettenmann H, Gotz M, Endres M. (2010) Modulation of fate determinants Olig2 and Pax6 in resident glia evokes spiking neuroblasts in a model of mild brain ischemia. Stroke; a journal of cerebral circulation 41(12) 2944-9 [DOI  PMID]

Boda E, Buffo A. (2010) Glial cells in non-germinal territories: insights into their stem/progenitor properties in the intact and injured nervous tissue. Archives italiennes de biologie 148(2) 119-36 [PMID]

Buffo A, Rolando C, Ceruti S. (2010) Astrocytes in the damaged brain: molecular and cellular insights into their reactive response and healing potential. Biochemical pharmacology 79(2) 77-89 [DOI  PMID]

de Luca A, Vassallo S, Benitez-Temino B, Menichetti G, Rossi F, Buffo A. (2009) Distinct modes of neuritic growth in purkinje neurons at different developmental stages: axonal morphogenesis and cellular regulatory mechanisms. PloS one 4(8) e6848 [DOI  PMID]

Lecca D, Trincavelli ML, Gelosa P, Sironi L, Ciana P, Fumagalli M, Villa G, Verderio C, Grumelli C, Guerrini U, Tremoli E, Rosa P, Cuboni S, Martini C, Buffo A, Cimino M, Abbracchio MP. (2008) The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PloS one 3(10) e3579 [DOI  PMID]

Buffo A, Rite I, Tripathi P, Lepier A, Colak D, Horn AP, Mori T, Gotz M. (2008) Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain. Proceedings of the National Academy of Sciences of the United States of America 105(9) 3581-6 [DOI  PMID]

Buffo A. (2007) Fate determinant expression in the lesioned brain: Olig2 induction and its implications for neuronal repair. Neuro-degenerative diseases 4(4) 328-32 [DOI  PMID]

Milasin JM, Buffo A, Carulli D, Strata P. (2007) Intensive remodeling of Purkinje cell spines after climbing fibers deafferentation does not involve MAPK and Akt activation. Annals of the New York Academy of Sciences 1096 230-8 [DOI  PMID]

Mori T, Tanaka K, Buffo A, Wurst W, Kuhn R, Gotz M. (2006) Inducible gene deletion in astroglia and radial glia--a valuable tool for functional and lineage analysis. Glia 54(1) 21-34 [DOI  PMID]

Buffo A, Vosko MR, Erturk D, Hamann GF, Jucker M, Rowitch D, Gotz M. (2005) Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair. Proceedings of the National Academy of Sciences of the United States of America 102(50) 18183-8 [DOI  PMID]

Mori T, Buffo A, Gotz M. (2005) The novel roles of glial cells revisited: the contribution of radial glia and astrocytes to neurogenesis. Current topics in developmental biology 69 67-99 [DOI  PMID]

Milasin J, Buffo A, Carulli D, Andjus P, Strata P. (2005) MAPK activation in cerebellar basket cell terminals after harmaline treatment. Annals of the New York Academy of Sciences 1048 411-7 [DOI  PMID]

Carulli D, Buffo A, Strata P. (2004) Reparative mechanisms in the cerebellar cortex. Progress in neurobiology 72(6) 373-98 [DOI  PMID]

Buffo A, Carulli D, Rossi F, Strata P. (2003) Extrinsic regulation of injury/growth-related gene expression in the inferior olive of the adult rat. The European journal of neuroscience 18(8) 2146-58 [PMID]

Carulli D, Buffo A, Botta C, Altruda F, Strata P. (2002) Regenerative and survival capabilities of Purkinje cells overexpressing c-Jun. The European journal of neuroscience 16(1) 105-18 [PMID]

Rossi F, Buffo A, Strata P. (2001) Regulation of intrinsic regenerative properties and axonal plasticity in cerebellar Purkinje cells. Restorative neurology and neuroscience 19(1-2) 85-94 [PMID]

Strata P, Buffo A, Rossi F. (2001) Regenerative events in the olivocerebellar pathway. Restorative neurology and neuroscience 19(1-2) 95-106 [PMID]

Buffo A, Zagrebelsky M, Huber AB, Skerra A, Schwab ME, Strata P, Rossi F. (2000) Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured purkinje cell axons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20(6) 2275-86 [PMID]

Strata P, Buffo A, Rossi F. (1999) Mechanisms of axonal plasticity. Archives italiennes de biologie 137(2-3) 181-92 [PMID]

Zagrebelsky M, Buffo A, Skerra A, Schwab ME, Strata P, Rossi F. (1998) Retrograde regulation of growth-associated gene expression in adult rat Purkinje cells by myelin-associated neurite growth inhibitory proteins. The Journal of neuroscience : the official journal of the Society for Neuroscience 18(19) 7912-29 [PMID]

Buffo A, Fronte M, Oestreicher AB, Rossi F. (1998) Degenerative phenomena and reactive modifications of the adult rat inferior olivary neurons following axotomy and disconnection from their targets. Neuroscience 85(2) 587-604 [PMID]

Buffo A, Holtmaat AJ, Savio T, Verbeek JS, Oberdick J, Oestreicher AB, Gispen WH, Verhaagen J, Rossi F, Strata P. (1997) Targeted overexpression of the neurite growth-associated protein B-50/GAP-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants. The Journal of neuroscience : the official journal of the Society for Neuroscience 17(22) 8778-91 [PMID]

Rossi F, Bravin M, Buffo A, Fronte M, Savio T, Strata P. (1997) Intrinsic properties and environmental factors in the regeneration of adult cerebellar axons. Progress in brain research 114 283-96 [PMID]

Verze L, Buffo A, Rossi F, Oestreicher AB, Gispen WH, Strata P. (1996) Increase of B-50/GAP-43 immunoreactivity in uninjured muscle nerves of MDX mice. Neuroscience 70(3) 807-15 [PMID]

Courses

• ANATOMIA E FISIOLOGIA DEI MODELLI ANIMALI (INT0649)
  Corso di Laurea in Biotecnologie
• Fisiologia I (INT0649C)
  Corso di Laurea in Biotecnologie
• NEURAL PLASTICITY AND BEHAVIOR CONTROL (SVB0200)
  Cellular and Molecular Biology
• NEUROPHYSIOLOGY (SVB0102)
  Cellular and Molecular Biology
• Neurology (SCB0217)
  MedInTO Medicine and Surgery
• Neurology - Module of Physiology (SCB0217A)
  MedInTO Medicine and Surgery
• Neurophysiology (NEU0268A)
  Biotechnology for Neuroscience
• Neurophysiology and neuropharmacology (NEU0268)
  Biotechnology for Neuroscience
• Physiological Basis of Human Body (SCB0203)
  MedInTO Medicine and Surgery
• Physiological Basis of Human Body - module of Physiological Basis of Human Body Mod. 1 (SCB0203A)
  MedInTO Medicine and Surgery
• Physiological Basis of Human Body - module of Physiological Basis of Human Body Mod. 2 (SCB0203B)
  MedInTO Medicine and Surgery
• Physiology of Systems (SCB0208)
  MedInTO Medicine and Surgery

Research topics

Annalisa Buffo ha maturato competenze e collaborazioni nell’ambito delle strategie per la riparazione dei danni cerebrali, interessandosi sia di rigenerazione assonale che di neurogenesi nel cervello adulto. Inoltre, ha avviato con la Prof.ssa Magdalena Goetz di Monaco di Baviera un filone di ricerca che guarda alla glia e ai progenitori presenti nel parenchima cerebrale come strumento di plasticità del sistema nervoso e di fonte endogena per la rigenerazione di oligodendrociti e neuroni.

Research groups

• Fisiopatologia delle cellule staminali cerebrali

Activities in agenda

See my calendar

Academic bodies

• Research Commission

• Commissione Terza Missione 2021-2024
• Consiglio di Dipartimento

Office hours

Previo appuntamento
Mercoledì ore 14:00-16:00
Dipartimento di Neuroscienze
Corso Raffaello 30
10125 Torino